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Arch Physiol Biochem 113:234258 Ghezzi P (2005) Regulation of protein function by glutathionylation

A recent study further demonstrated that proline catabolism via PRODH supports 3D growth of breast cancer cells, with elevated PRODH expression and proline oxidation in metastatic lesions compared with primary tumors, thereby promoting metastatic colonization and identifying PRODH as a potential target for metastasis suppression 64

doi: 10.1016/j.clim.2019.03.009 102 LeeS-HChangDKGoelABolandCRBugbeeWBoyleDLet al

If receiving cancer treatment, supplementing with Glutathione may cause drug interactions and allow cancer cells to be resistant to chemotherapy drugs, thus decreasing their effectiveness and increasing oxidative stress

Another study 4 found that the use of NAC during IVF could improve the quality of blastocysts in advanced-age women

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