In addition to extensive descriptions of abnormalities in immunometabolism of vitiligo, recent studies support the critical role of dysregulation of metabolic pathways in various skin immune cells, including keratinocytes, tissue-resident memory T cells, and innate lymphoid cells of vitiligo pathogenesis
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Magder S (2006) Reactive oxygen species: toxic molecules or spark of life
Most patients find treatment straightforward, well-tolerated, and effective over time when combined with appropriate lifestyle support
It also modulates the FAK-paxillin pathway to drive fibroblast spreading and migration
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