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doi: 10.3389/fimmu.2022.837524 29 CalabreseE

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Consistency is essential

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Clinicians use fasting serum IGF-1 (target: age-adjusted mid-normal range) as the primary efficacy marker, making any drug that independently alters hepatic IGF-1 output a source of confounding

Because of this, the quality of compounded drugs can vary significantly from one pharmacy to another