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A Review of the Pharmacokinetics of Levothyroxine for the Treatment of Hypothyroidism

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If its a question of side effects, many times lowering the dose, titrating up very slowly, and adding medications to help with the side effects can help quite a lot, she said

124 Moreover, many peptide drugs are not known to be substrates or inhibitors of transporters at present, indicating that transporter-mediated biliary or renal excretion may not be a major pathway for their elimination