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Low vitamin B12 can lead to multiple dermatological symptoms such as hyperpigmentation, discoloration of nails, vitiligo, changes in hair, and angular stomatitis

Health Aff (Millwood) 30(5):842

Of note, the extent of the demonstrated beneficial effect on recovery of muscle function and integrity is considerable, and involves the transection- (15, 37) crush- (16, 17) lesion of striated muscle, and healing impairment induced by systemic corticosteroid application (16), as well as function impairment induced by centrally acting agents (74, 75)

4 support this prediction

Skin problems affect up to 15% of people with IBD

Useful experimental controls may include vehicle-treated controls, positive controls for migration or angiogenesis, pathway inhibitors for NO or FAK-related signaling, and analytical confirmation of peptide identity and purity