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After OGD treatment, the number of Ki-67-positive endothelial cells significantly decreased, while the intracellular expression levels of senescence markers P21, P53, and the DNA damage indicator -H2AX were markedly elevated (Figure 3B)

Loss of these beneficial microbes could reduce Treg abundance, tilting the immune system toward a pro-inflammatory phenotype [66]

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Depending on the reason for the nephrostomy and how quickly your body heals, the nephrostomy tube may be used for different lengths of time