Peter : Don't ask me about ApoE
The glutathione peroxidase family: Discoveries and mechanism
Xu M, Bhatt DK, Yeung CK, Claw KG, Chaudhry AS, Gaedigk A, Pearce RE, Broeckel U, Gaedigk R, Nickerson DA, et al
While most intracellular glutathione is in a reduced state (GSH) with approximately 1% as an oxidized form (GSSG), this proportion can decrease in response to a variety of cellular stressors, including heavy metals, high glucose concentrations, poor nutrition, heat shock, reactive oxygen and nitrogen species, cigarette smoke, and other toxins including persistent organic pollutants
In fact, there is a slight increase in the number of patients taking SGLT2s after they start on GLP1s
doi: 10.1007/S12020-021-02945-1 57 KatoleNTSalankarHVKhadeAMKaleJSBankarNJGosaviPet al