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Its mechanism slows digestion, which may help some with IBS-D but can significantly worsen symptoms for those with IBS-C

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Additionally, probiotics improve the integrity of the intestinal barrier by increasing mucus production and tight junction proteins, which help lower intestinal permeability and prevent the entry of harmful substances like lipopolysaccharides (LPS) into the bloodstream

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7 A cystic duct remnant is also possible, potentially leading to stone formation, causing Mirizzi syndrome