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Specifically, the dithiol groups of Trx(SH) 2 can directly reduce oxidized proteins or provide electrons to thiol-dependent peroxidases (Prx) to convert hydrogen peroxide to water
Charlton M, Sreekumar R, Rasmussen D, Lindor K, Nair KS (2002) Apolipoprotein synthesis in nonalcoholic steatohepatitis
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John s Wort induces CYP3A4 and can reduce plasma concentrations of PPIs like omeprazole, while curcumin and berberine can inhibit CYP3A4 and P-glycoprotein, raising toxicity risks with drugs such as warfarin, statins, or immunosuppressants
Most are given as small subcutaneous injections that patients can self-administer at home, and some come in oral or other forms
Summary Glutathione is a potent antioxidant, and we need to maintain high antioxidant levels to fight oxidative stress from environmental toxins and aging
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