tirzepatide non responder Why Doesn't Work for Some People: Causes and Solutions When Weight-Loss Drugs Don't Work

Berinstein E, Levy A

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The primary endpoint was the percent change in visceral adipose tissue (VAT) on CT

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It enhances blood sugar control, lowers blood pressure, and optimizes cholesterol levels, reducing the risk of chronic diseases

While these drugs were not initially approved for weight management, a small proportion of patients were using them to support weight loss, with doctors prescribing these off-label (off-label prescribing is where a drug is prescribed for a reason other than the one it is licensed for) in these cases, GLP-1RAs were given to people without diabetes but with a high body mass index (BMI)