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2025;39(2):e1534

Hericum erinaceus , also known as "Lions Mane" due to its unique appearance, is a leading medicinal mushroom in mycotherapy and widely appreciated in Asia for its health benefits

That doesnt mean its one-size-fits-all

Certain drugs are notorious for causing pigmentation changes: Antimalarial medications (like chloroquine and hydroxychloroquine) Minocycline (a tetracycline antibiotic) Some chemotherapy drugs Certain antipsychotic medications If you've recently started a new medication and notice your gums darkening, it's worth mentioning to your doctor or dentist

the 2016 Radiology randomised double-blind fMRI study in healthy adults (a single low dose lifted memory retrieval ~7%)

This dual-pathway independence allows the compound to act synergistically with GHRH analogues in experimental models