Treatment of vitamin B12 deficiency
While singly-housed animals may experience stress that impacts metabolism, body weight, and adiposity 65,66,67,68,69 , the singly-housed animals in this study were treated identically (to the best of the experimenters ability) to minimize and equalize stress across all animals and reduce confounding variables
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May support weight loss by enhancing metabolic activity in fat cells
Additionally, the applicant asserted that the specific substantial clinical improvement claim addressed by Geldmaker et al