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Similar content being viewed by others Introduction Tirzepatide (TRZ) is an analog of the gastric inhibitory polypeptide (GIP) and acts as a dual agonist for glucagon-like peptide 1 (GLP-1) and GIP receptors (Rhea et al

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Currently, this endosomal escape process remains highly inefficient, representing a critical barrier to achieving potent and sustained target degradation (Table 2) [222, 223]

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