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Lower inflammatory burden might theoretically benefit inflammatory skin conditions, though the magnitude of this effect on acne specifically remains uncertain

402 The primary outcome, the PSQI total score, improved by about 21% in the saffron group while worsening by about 9% with placebo

doi: 10.1186/1471-2350-9-62

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4.1 Thyroid function The PTU-induced hypothyroid group showed significantly lowered plasma T3 and T4 levels accompanied by significantly higher plasma TSH levels than the control rats

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