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In 2023, Lilly had seven blockbuster drugs, led by its two top-selling products, Trulicity (dulaglutide) with revenues of $7.13 billion, and Mounjaro (tirzepatide) with sales of $5.16 billion, both GLP-1 drugs

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However, the number of GLP-1 receptors in these tissues remained unchanged

Lastly, the authors also state 2 analysis methods (trial product and treatment policy estimand), but, for example, only the trial product estimand results were shown for the reduction in fasting plasma glucose and the proportion of patients achieving hemoglobin A1C lower than 6.5%

Conventions as in Fig 1C