The gut microbiota produces an array of bioactive metabolites, such as short-chain fatty acids (SCFAs), neurotransmitter precursors, and uremic toxins, that mediate communication between the gut, brain, and kidneys (Lin et al., 2025)
SENDs significantly upregulate the mRNA expression of GPX1 in pancreatic tissues of T2DM mice established using a high-fat diet and streptozotocin (STZ) treatment, increases protein expressions of Parkin, PINK1, and LC3-II/I, restores pancreatic mitophagy, and significantly reduces the mRNA expression of glucose-regulating protein 78 (GRP78), protein kinase R-like endoplasmic reticulum kinase (PERK), eukaryotic initiation factor-2 (eIF-2), activating transcription factor 4 (ATF4) and C/BEBP homologous protein (CHOP), and effectively inhibits ERS and apoptosis
NICE guidance emphasises the importance of patient-centred care and shared decision-making in obesity management
instead, we facilitate access to the medical professionals who provide that supervision
Levothyroxine is used to treat hypothyroidism (a condition where the thyroid gland does not produce enough thyroid hormone)
Supplementation of nanoselenium in fish diet: Impact on selenium assimilation and immune-regulated selenoproteome expression in monosex Nile tilapia ( Oreochromis niloticus )
