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While quite efficacious, these medications are quite expensive, with list prices ranging from $12,000 annually to roughly $16,000 annually as of March 2025, according to the September budget request from the states health and human services office

In a retrospective study GLP-1 agonists have been shown to be associated with lower rates of hepatic decompensations compared to other glycemic agents, although more prospective data is needed

Meanwhile, GLP-1R has been shown to exist in human liver cells

In general, try to limit or avoid: Adjusting to a GLP-1 while changing your diet may be overwhelming

The inconvenience of slightly extra luggage weight pales compared to running out of medication far from home

I want that baseline, because if were going to drive significant fat loss, I want to understand what thats going to mean for her specifically not just her weight, but how shes going to feel. That standard a hormonal baseline before starting, and monitoring as loss progresses is not yet common practice