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Usually, these are absorbed as part of a healthy, balanced diet, but some people can find themselves deficient for all sorts of reasons, including auto-immune conditions and genetics, as well as environmental factors

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GLP-1 medications are generally not recommended for patients with type 1 diabetes, those with a personal or family history of medullary thyroid carcinoma, or individuals with multiple endocrine neoplasia syndrome type 2

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On legality: it was never FDA approved, partly because its lethal dose is unknown