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Ans: Lethargy, poor appetite, weight loss, a dull coat, skin issues, and anemia can all point toward low B12 levels in pets

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NQO1, a reductase that can maintain antioxidant forms of CoQ10, -tocopherol and ascorbic acid, plays an important role in maintaining antioxidant protection and inhibiting lipid peroxidation

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Acta Pharmacol Toxicol 59(Suppl 7):450453 James SJ, Cutler P, Melnyk S, Jernigan S, Janak L, Gaylor DW, Neubrander JA (2004) Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism