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Ongoing research will clarify optimal dosing and long-term safety
Similarly, in the FIGARO-DKD trial (Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease trial), the residual risk of the primary composite end point of death from CV causes, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure was 12.4% [11, 13]
Syncope, gastrointestinal side effects, dizziness, xerostomia, confusion, hallucinations, tremor, sexual dysfunction, and bleeding risk have been reported as adverse effects of the sertraline
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While generally considered safe, berberine may interact with certain medications, so consulting with a healthcare provider before starting is recommended