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Severe bleeding disorders are rare contraindications to injectable GLP-1 therapy, but your provider needs to know your full medical history

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Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation

Several studies evaluated the ingestion of up to 15 g of guar gum or pectin with each meal to slow gastric emptying, reduce the release of gastrointestinal hormones, improve hyperglycaemia and control symptoms of dumping syndrome 45,100,101,102,103,104,105,106

Given the duration of evidence, low cost, favorable safety profile, and background use in recent CVOTs, metformin has, until now, remained first-line therapy onto which additional agents can be considered for cardiovascular risk reduction in T2DM