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A serum APAP concentration (measured at least 4 hours after ingestion) resulting in a value above the lower line of the nomogram necessitates a full course of NAC therapy (eg, standard oral loading dose of 140 mg/kg of NAC followed by 70 mg/kg every 4 hours for 17 oral doses) be delivered

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It is a question that the team hopes to explore in follow up studies focused specifically on substance use disorder.

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When hunger keeps returning between meals, portions creep up, and staying inside a calorie target starts to feel impossible