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Lin Z, Fang D (2013) The roles of SIRT1 in cancer

Due to shallow tissue penetration of many GGT-targeted fluorescent probes, their clinical application is limited

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Another vital area for future exploration is temporal control over gene editing activity, which could be achieved using inducible Cas9 systems responsive to small molecules or external stimuli (light or ultrasound), thereby adding a layer of control to enhance safety and efficacy

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