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10.1172/jci.insight.159863 JCI Insight 43 KoekkoekP.KappelleL.van den BergE.RuttenG.BiesselsG

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The inclusion of Black Pepper Extract (Bioperine) ensures maximum nutrient uptake

We highly suspect that GLUT4, which participates in epithelium glucose uptake and transport, not only contributes substantially to the glucose microenvironment in the uterine fluid but is also important for adequate glucose uptake of cells of the uterus per se to reach the state of uterine receptivity, therefore interfering with subsequent implantation