Each has its own pros and cons, and what works for your best friend might not be the best fit for you
Sermorelin and GLP-1 agonists are entirely different peptide classes
Shuaibin Zhang, Bing Zhou, Yanyuan Kang, Xia Cui, Ao Liu, Angelique Deleris, Maxim VC Greenberg, Xiekui Cui, Qi Qiu, Falong Lu, James A Wohlschlegel, Steven E Jacobsen and Xiaofeng Cao, "C-terminal domains of histone demethylase JMJ14 interact with a pair of NAC transcription factors to mediate specific chromatin association", Cell Discovery 1 (15003): 1-13 (2015)
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53 In longer studies of 612 months ( n = 2887), combining 5002000 mg/day metformin with various COCPs led to greater reductions in FAI, free testosterone, and inflammatory markers, and improvements in body composition, facial hirsutism, vascular function, and aortic elasticity than either treatment alone, although no additional benefits were seen for lipids, insulin sensitivity, SHBG, or testosterone beyond those provided by COCPs alone
The disproportionate occurrence of GI AEs may have lead to unblinding and contributed bias to patient-reported outcomes such as HRQoL and safety outcomes