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For patients without absorption disorders, high-dose oral supplements of 1,000 to 2,000 mcg daily have been shown to be comparably effective at correcting mild to moderate deficiency at lower cost and greater convenience.

For example, instead of 1.0 mg once weekly, they inject 0.5 mg on Monday and 0.5 mg on Thursday

In addition to standard vitamin B12 nutritional supplements, gummy vitamins and liquid vitamins are also available for people who can't tolerate pills

(Nephrology) Office visit for a 42-year-old, established patient, to read tuberculin test results

Do not self-prescribe high-dose B12 based on non-specific symptoms like fatigue without medical assessment

It may also enhance the activity of certain immune cells, which may ward off viruses and chronic disease such as cancer, according to a 2020 review in the medical journal, Nature (2)