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clinical presentation of high-risk (massive) poisoning Patients develop mitochondrial dysfunction very early (usually within 30 grams) may present with mental status alteration and lactic acidosis within 12 hours of ingestion

CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD+/NADH ratio and Sirt3 activity in renal tubular cells in diabetic rats

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