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A review highlighted that changes in lipid metabolism and mitochondrial dysfunction may be key factors contributing to cognitive dysfunction in diabetic patients (Potenza et al., 2021)

Many of these are approved for the treatment of type 2 diabetes, and some are approved for weight loss

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The comparison to Tirzepatide is closer, with Tirzepatide showing slightly better tolerability but lower efficacy

Because it was associated with excessive urine, ancient Greek physicians called the disease 'diabetes, which they took from the Greek word for 'siphon to reflect their observation that fluids flowed through diabetic patients like a siphon (Harris)

8.0%), constipation (14.0%, 16.2%, 16.8% vs