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Primary carnitine deficiency due to a failure of carnitine transport in kidney, muscle, and fibroblasts

A major cause of CKD is type 2 diabetes, with nearly 40% of people with diabetes also developing kidney disease

The compound acts as a precursor to Nicotinamide Adenine Dinucleotide (NAD+), an essential coenzyme present in all living cells, crucial for metabolic processes and cellular repair

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Although recent studies revealed the benefits of LC supplementation in a variety of conditions even in critically ill patients, a lack of knowledge on the results of LC supplementation in sepsis persuaded us to design a novel trial