Clinical & Medical Information The dosing protocols for retatrutide are not yet established and remain under continued clinical assessment
Methods This analysis mapped ICD-10 codes to the clinical criteria specified by CMS for the Medicare GLP-1 Bridge and utilized the 2023 20% Research Identifiable File (RIF) Medicare Fee-For-Service Claims and Medicare Advantage Encounter Data to create condition flags, along with the Part D Prescription Drug Event data to create a flag for GLP-1 use
Ozempic, Wegovy, Zepbound, Mounjaro: These medications have been a lifeline for millions of people, well beyond weight loss
At negative 20 degrees Celsius or colder, lyophilized retatrutide remains stable for up to 48 months
Expert Featured In This Story Stuart Phillips Professor Stuart Phillips is a professor of Kinesiology and the Tier 1 Canada Research Chair in Skeletal Muscle Health
Clinical Trial Efficacy Data The approval is backed by two pivotal Phase 3 trials within the CORALreef clinical program evaluated at week 24: CORALreef Lipids Trial: Achieved a statistically significant 56% placebo-adjusted reduction in LDL-C (with a post-hoc analysis showing a 60% reduction when biological inconsistencies were removed)
