The largest Wegovy trial (STEP program) reported an average ~15% body weight loss, which is markedly higher than results from older drugs like orlistat or appetite suppressants (typically 510%)

Resources and Next Steps Professional Organizations Academy of Nutrition and Dietetics Pediatric Nutrition Practice Group The Obesity Society Pediatric Obesity Section American Academy of Pediatrics Obesity guidelines and resources Pediatric Endocrine Society GLP-1 position statements Key Research and Guidelines AAP Clinical Practice Guideline for Obesity (2023) Pediatrics: GLP-1 Receptor Agonists in Pediatric and Adolescent Obesity (2025) NEJM: Semaglutide in Adolescents with Obesity (2022) CMAJ: Canadian Pediatric Obesity Guidelines Continuing Education Opportunities CDR Certificate of Training in Obesity for Pediatrics and Adults Board Certification in Pediatric Nutrition (CSP) Board Certification in Obesity and Weight Management (CSOWM) University-based certificate programs in pediatric weight management Stay Current Set up PubMed alerts for GLP-1 AND pediatric Follow pediatric endocrinologists on social media Join the Pediatric Nutrition Practice Group listserv Attend ObesityWeek for the latest research Your Next Steps Assess Your Current Knowledge: Take stock of what you know about GLP-1 medications and identify any knowledge gaps.s Choose Initial Training: Begin with free resources, such as podcasts and webinars

Symptoms may also appear after increasing the dosage because the digestive system must adjust again
In a study on 26 people prone to recurring cold sores, researchers suggested that a daily dosage of 1,000 mg may have reduced the subjects cold sores (x)
In contrast to this result, another recent study by Kovarik et al
Vitamin B12 and bariatric surgery After gastric bypass and sleeve gastrectomy surgery, absorption of vitamin B12 from food and oral supplements is compromised as the substance produced by the stomach which helps you to absorb the vitamin B12 is significantly reduced or even totally absent