Recchione, C
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Its important to know the difference between GLP-1s effects and gastroparesis
Of the plethora of articles retrieved from the second MEDLINE search, we identified 28 systematic reviews of animal stud-ies, [39-41] GSH-related genetic polymorphisms linked to various cancers (colorectal can-cer, [42] leukaemia, [43,44] lung cancer,[ 45,46] bladder cancer, [47] gastric cancer, [48,49] prostate cancer, [50-53] adult brain tumours, [54] basal cell carcinoma [55] ) and linked to other disorders (autism, [12, 13] hypertension, 56,57 respiratory diseases, [58,59] cataract, [60] myelodysplastic syndrome, [61,62] glioma [63] and male idio-pathic infertility.[ 64] ) There were 9 RCTs identified from two systematic reviews of the use of GSH to reduce chemotherapy-induced toxicity (6 cisplatin, 2 axaliplatin, 1 platinum)
As above commented, riboflavin serves as a cofactor for glutathione reductase (GR), the enzyme responsible for converting oxidised glutathione (GSSG) into GSH, so that riboflavin insufficiency increases their risk of developing cataracts in the elderly [107]
In Africa, GLP-1 access is currently limited primarily to private healthcare patients in South Africa, Nigeria, and Kenya, constrained by cost barriers that are not addressable without biosimilar entry or government subsidy programs
