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A more recent RCT similarly compared PEG with lactulose for treatment of overt HE in 100 patients with post-hepatitis C cirrhosis admitted for HE

Changes in levels of plasma DPP-4 activity could, therefore, be related to overall changes in the total expression of DPP-4 and/or simply altered shedding from cell membranes

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B12 deficiency is surprisingly common in the general population, and the metabolic changes triggered by tirzepatide can amplify that deficiency