As a result, Treg function may be negatively impacted, allowing for increased effector T cell function and subsequent secretion of the pro-inflammatory cytokines tumor necrosis factor (TNF) and IFN (89)
Methionine is converted into SAM by a process that requires energy
Sodium chloride-enriched diet enhanced inflammatory cytokine production and exacerbated experimental colitis in mice
Sikiric, P., Rucman, R., Seiwerth, S., et al
This proposed connection to GILZ-mediated signalling could help explain DSIPs anti-inflammatory effects and its capacity to modulate immune function, though this remains a hypothesis under investigation
Research Areas of Interest