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In comparison, PICU patients from the current study (mean E h Cys/CySS 65 mV) have a significantly more oxidized Cys/CySS redox potential than mild-to-moderate asthmatics (mean E h Cys/CySS 95 mV) and are similarly oxidized to severe asthmatics in the Fitzpatrick study (mean E h Cys/CySS 55 mV)

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However, advancing GR as an antimicrobial target necessitates addressing potential challenges, such as ensuring the specificity of bacterial GR inhibitors to avoid affecting host cells

Singh CSB, Choi KB, Munro L, Wang HY, Pfeifer CG, Jefferies WA

This means there is less specific evidence on using stem cells in orthobiologics