Clinical studies have proven that there has been a significant decrease in body weight for participants using semaglutide GLP-1 compared to those on a placebo
doi:10.1007/s40265-020-01260-9
GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) begin affecting appetite and blood sugar within days to weeks, but clinically meaningful outcomes develop more gradually
So far, the most common side effects seen in clinical trials have been digestive symptoms, such as nausea, vomiting, diarrhoea, constipation, bloating, burping and indigestion
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It is meant to be used alongside a reduced-calorie diet and increased physical activity, not as a standalone fix