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If a tablet is scored, splitting may still depend on the product label and pharmacist guidance

doi: 10.3389/fphys.2020.00012 26 HuoZ.YuL.YangJ.ZhuY.BennettD

Gastrointestinal symptoms including nausea, vomiting, and diarrhea are most common, particularly during dose escalation

Adverse Gastrointestinal Effects of GLP-1 Receptor Agonists . National Library of Medicine

Semaglutide and tirzepatide bind to GLP-1 receptors in the hypothalamus and gastric smooth muscle, extending the postprandial satiety window from 90120 minutes to 46 hours

Cortex 46 DoetschF.Garcia-VerdugoJ