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Specifically, the trial reported an average weight loss of 17.5% and 24.4% at 24 and 48 weeks, respectively

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The side effects are real annoying at best and debilitating at worst and can include nausea, diarrhea, cramps and abdominal pain, constipation, vomiting, gastroesophageal reflux, gastroenteritis, pancreatitis, gastroparesis, intestinal obstruction, gall bladder disease, headaches and potential risk for certain types of thyroid and endocrine cancers, among other adverse effects

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Author contributions AB, NK, AK, RK, SR, JO, KS, CS, and SS contributed to the techniques and generated data