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Researchers first identified it decades ago and later discovered that levels tend to decline with age

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No TEAEs were reported in the severe hepatic impairment group (Table 6)

Using theoretical calculations and pseudo-ternary phase diagrams, we designed and constructed a thermodynamically stable ionic liquid (IL)-based microemulsion (IL-M), which integrates the high drug solubility of ILs and high skin permeability of microemulsions, thus improving the local delivery of copper peptides by approximately three-fold while retaining their biological function

Pathogen-derived toxins and immune disruption Pathogens that dominate chronic wounds, particularly those embedded in biofilms, play a central role in exacerbating tissue damage and maintaining a persistent inflammatory state