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At 2 h post treatment, mice were injected intratracheally with either vehicle control (ethanol) or 25HC (5 mg/kg)

This finding indicates that exendin 2029 does not activate GLP-1R (Supplementary Fig

doi: 10.1016/j.chembiol.2008.02.010 13 WeiZXieYWeiMZhaoHRenKFengQet al

It is proposed that this specific peptide sequence may have a significant impact on cellular communication processes, specifically targeting fibroblasts

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These changes may result in muscle mass reduction, potentially leading to osteosarcopenia, which could increase the risk of fracture owing to an elevated likelihood of falls