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Given the importance of these cells in fighting cancer, their exhaustion leads to decreased responsiveness to stimuli, low cytotoxicity, poor IFN- secretion, and thus compromised ability to kill tumour cells (149151)

Reason 2: Unrealistic weight-loss expectations

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The FDA has approved certain GLP-1s as a treatment for obesity, defined as someone who has a body mass index (BMI) of 30 or over