is there a difference between semaglutide and tirzepatide vs Tirzepatide vs. Semaglutide: Which Weight

Semaglutide targets the hypothalamus, the part of the brain that regulates hunger and desires

doi: 10.1038/s41569-023-00849-3 46 GongBLiCShiZWangFDaiRChenGet al

Treatment of Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia

Jump to: Side effects by dose | Stomach and gut side effects | Heart rate and irregular heartbeats | Dysesthesia: skin sensation changes | Muscle loss during rapid weight loss | Mental health and mood | Drug interactions and contraception | Other side effects | How retatrutide compares to Mounjaro and Wegovy | Discontinuation and weight regain | What we dont yet know | When to speak to a healthcare professional | FAQ | Take home message | Second Natures Mounjaro programme | References Retatrutides side effects fall into three main groups: stomach and gut symptoms during dose increases, a heart-rate increase larger than other GLP-1 medications, and a skin sensation called dysesthesia that emerged at higher doses in Phase 3 trials

doi:10.1056/NEJMoa2511774

Some debate exists about long-term use since obesity tends to be chronic, these medications likely need to be continued to maintain weight loss (as stopping leads to regain, based on observations)