Furthermore, the study evaluated a battery of immune markers as secondary outcomes to assess its broader effects
We also used a self-controlled case series design [19], which comprised of new users of GLP-1 RAs ( n = 85,717 ) or SGLT-2 inhibitors ( n = 78,366 ) or DPP-4 inhibitors ( n = 35,762) from 2014 to 2022
With advancing age, carnitine levels decline in all our tissues
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The pre-specified secondary outcomes were (1) all cause-mortality and (2) incidence of a cardiovascular composite event outcome that included: first occurrence of acute myocardial infarction, cardiac arrest or ventricular fibrillation, acute stroke, or coronary revascularization, as previously described and validated using validated International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) and 10th Revision, Clinical Modification (ICD-10-CM) and procedure codes 52,53,54
