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The authors proposed multiple potential mechanisms including interactions with opioid, GABAergic, and monoaminergic systems, establishing the conceptual framework for subsequent mechanistic research into DSIP's neurophysiological actions

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[DOI] [PMC free article] [PubMed] [Google Scholar] 188.Hurrle S., Hsu W.H

This makes it a safer alternative for those seeking skin lightening products that won't compromise skin health

If thinning is diffuse rather than focal, systemic subcutaneous injection may outperform scalp-specific delivery