4.2.1 Chemical drug-induced liver injury Glycyrrhizin activates the -catenin signaling pathway, upregulates proliferation-related proteins (such as Proliferating Cell Nuclear Antigen (PCNA), Cyclin D1, and Cyclin-Dependent Kinase (CDK) 4), promotes hepatocyte proliferation and liver tissue regeneration, thereby effectively alleviating acetaminophen-induced acute liver injury and significantly reducing acetaminophen (APAP)-elevated serum ALT and AST levels (Xia et al., 2025)
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A recent single-cell RNA-sequencing analysis showed that metformin increases the differentiation of neural stem cells and expands the population of neural stem cells and oligodendrocyte precursors in APP/PS1-AD mice (Qiu-Yue et al., 2022)
L-Glutathione reduces oxidative stress to improve your overall complexion