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N Engl J Med 390(15):13941407 Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ et al (2024) Semaglutide and NT-proBNP in obesity-related HFpEF

IGF-1 LR3, by contrast, acts directly on all tissues expressing IGF-1 receptors, producing less tissue selectivity

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Opioid mu, delta and kappa receptor-induced activation of phospholipase C-3 and inhibition of adenylyl cyclase is mediated by G and G i 2 in smooth muscle

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