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Nausea: 50-66% Diarrhea: 49% Vomiting: 41% Dyspepsia: Elevated risk Discontinuation due to side effects: 15.9-20% The higher side effect rates for Survodutide require context
Third, add a gentle carb
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While both agents struggled with the inherent GI burden typical of GLP-1RAs, efpeglenatides limitations were largely dose-related and within manageable expectations, whereas taspoglutides combination of severe immunogenicity and hypersensitivity reactions rendered it clinically unviable
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10.1007/s00018-024-05507-6 25 DanpanichkulP.SuparanK.DiazL
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