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Intranasal treatment of lixisenatide attenuated emotional and olfactory symptoms via CREB-mediated adult neurogenesis in mouse depression model

Blum cautions against prefilled syringes from doctors offices and telehealth companies

It mimics the glucagon-like peptide-1 hormone your gut naturally releases after eating

The serendipitous discovery of exendin-4 led to the development of exenatide immediate-release (exenatide IR, Byetta), a synthetic version of exendin-4 with C-terminal amidation to enhance its stability [ Figure 2 , Table 1 ], which became the first FDA-approved GLP-1RA in 2005 for the treatment of T2DM in adults [ Table 2 ]

Healthy weight loss with either therapy requires careful monitoring and realistic goal setting

Step 5: Hold steady