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When HCG is administered alongside other fertility treatments, such as clomiphene citrate or menotropins, the risk of ovarian hyperstimulation syndrome (OHSS) increases, requiring careful monitoring by reproductive specialists

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However, NCLER admits that these evaluations are limited, and that more data is needed

Serious adverse events remain rare in non-diabetic populations when medications come from licensed 503A compounding pharmacies with proper quality controls

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