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Tirzepatide is a dual GIP/GLP-1 receptor agonist designed to engage two hormone signaling pathways involved in appetite regulation and metabolic response

the latter may produce hydrogen sulfide through sulfate reduction, potentially exacerbating intestinal inflammation and contributing to stereotyped behaviors ( Bifidobacterium not only impairs the synthesis of SCFAs but is also associated with decreased serum levels of folate and vitamin B12

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MPNST (previously known as neurogenic sarcoma, neurofibrosarcoma, or malignant schwannoma) is a relatively rare malignant tumor, accounting for 510% of all soft tissue sarcomas with an incidence rate of 0.001% in the general population and 4.6% in patients with NF1 [7]

doi: 10.1073/pnas.0908876106 75 KaplanG

Microbial influences on urinary polyamine excretion